A Disposable Multianalyte Electrochemical Immunosensor Array for Automated Simultaneous Determination of Tumor Markers
نویسندگان
چکیده
منابع مشابه
A disposable multianalyte electrochemical immunosensor array for automated simultaneous determination of tumor markers.
BACKGROUND Automated and convenient multianalyte detection with high throughput is increasingly needed in clinical diagnosis. We developed a disposable 4-by-2 array for programmed simultaneous amperometric immunoassay of 4 tumor markers. METHODS We used a screen-printed technique, 1-step immobilization method, and flow injection technique. We immobilized carcinoembryonic antigen, alpha-fetopr...
متن کاملDisposable reagentless electrochemical immunosensor array based on a biopolymer/sol-gel membrane for simultaneous measurement of several tumor markers.
BACKGROUND A reagentless sensor array for simultaneous multianalyte testing (SMAT) may enable accurate diagnosis and be applicable for point-of-care testing. We developed a disposable reagentless immunosensor array for simple immunoassay of panels of tumor markers. METHODS We carried out SMAT with a direct capture format, in which colloidal gold nanoparticles with bound horseradish peroxidase...
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A novel electrochemical immunosensor array for the simultaneous detection of multiple tumor markers was developed by incorporating electrochemically addressing immobilization and one signal antibody strategy. As a proof-of-principle, an eight-electrode array including six carbon screen-printed working electrodes was used as a base array for the analysis of two important tumor markers, carcinoem...
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An ultrasensitive multiplexed electrochemical immunoassay method was developed for the detection of tumor markers by combining a newly designed trace tag and a disposable immunosensor array. The array was prepared by immobilizing capture antibodies on gold nanoparticles which were assembled on carbon nanotubes-chitosan modified screen-printed carbon electrodes. The trace tag was prepared by loa...
متن کاملDisposable immunosensor for the determination of domoic acid in shellfish.
The construction of an electrochemical immunosensor coupled to differential pulse voltammetry (DPV) for the detection of domoic acid (DA), a neurotoxic aminoacid responsible for the human syndrome known as "Amnesic Shellfish Poisoning" (ASP), is proposed here. The method involves the use of disposable screen-printed electrodes (SPEs) for the immunosensor development based on a "competitive indi...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2007
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2007.086975